Regennica is a family of cell delivery mechanisms incorporating biologic and synthetic materials. Some are designed to be formulated with limited effort, such as mixing in a syringe just prior to injection, while others are more complex requiring computer assisted bioprinting with laser polymerization of photosensitive materials, extrusion of temperature cured thermoplastics, or chemical and heat sensitive biological proteins. All formulations are designed to maximize the potential benefit of the cell transplant by:
• Maintaining the maximum achievable cellular viability
• Providing a permissive environment for cellular proliferation
• Creating an ideal microenvironment for the intended use that permits mechanotransduction and mechanosensing, and
• Controlling the rate of cellular migration from the implant into the
damaged tissue
Proprietary Materials
Cascia is developing two proprietary additives to enhance the function of our implants.
Small molecule
• Inhibits promotion of fibrosis
• Reduces early cell migration out of the implant
• Permits stem cell self-replication in situ • Limits premature cell differentiation
Small molecule
Cascia
