Cascia
leverages the power of artificial intelligence to create customized therapies
for patients with complex medical conditions.
We are advancing stem cell therapies into the clinic by integrating
proven technologies to enhance the quality and efficacy of our treatments
including reactive artificial intelligence. AccelThera,
our computerized workflow solution, prepares cellular preparations that are
tailored to each patient and their immediate therapeutic needs.
AccelThera exchanges information with
medical instrumentation, processing equipment, and testing devices to ensure
that the complex calculations required to prepare each batch are done properly
and in accordance with our quality standards. Reactive artificial intelligence is rules-based and is ideally suited to performing predefined tasks, such as automating workflows for repetitive tasks where efficiency and precision are crucial. Emerging frameworks, such as generative AI, produce unique output using unsupervised learning techniques. While generative AI holds much promise for the future, it is not yet sufficiently reliable for application to healthcare decision making without "humans in the loop" to ensure that a human with relevant expertise is involved in any decisions that affects a patient. We focus on using AI to reduce the workload and to improve the quality of decision making by our medical scientists without compromising patient safety.
Image recognition of cell products for quality control and to identify rare phenotypes. We routinely use flow cytometry analysis to inspect a sample of the cell product that we are going to send to the operating room, and the instrument captures a microscopic image of thousands of cells as they pass through the detector. This provides both improved quality control and allows us to capture images for training future algorithms.
Biometrics allow our technicians and medical scientists to interact with technology without physically interacting with the equipment. Voice commands, transmitted via headsets, substitute for the use of keyboards that might spread pathogens, and use of facial and iris recognition protects our computing resources and limites physical access to our offices, research laboratories, and processing centers.
IoT technology (the “Internet of Things”) enables us to maintain a consistent level of quality control across all of our locations. AccelThera interfaces with various monitoring devices in the processing center and operating room. IoT enabled equipment transmits telemetry reading periodically so that we can remotely track various equipment, parameters such as schedule maintenance time or temperature excursions of our refrigeration units during a power failure.
Photopolymerization of materials when constructing implants enables us to modulate the tensile strength and to program the period of resorbtion. These parameters affect how the cells behave after they are transplanted into the patient, but the optimal wavelength to use and the desired, laser pulse energy is specific to each patient.
Designing implants to repair hard tissues can be accomplished by 3D modeling software that is part of our bioprinting solution. The software allows us to import DICOM (Digital Imaging and Communications in Medicine) files from MRI, CT scans, or X ray machines, and convert them to stereolithography commands for use in the bioprinter.